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Basic information

CohesinDB ID: CDBP00419122

Locus: chr21-38242575-38246729

Data sourse: ENCSR000BTQ, ENCSR000EFJ, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE72082, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE85526, GSE135093, GSE206145-NatGen2015, GSE68388, GSE73207, ENCSR703TNG, GSE126755, GSE165895

Cell type: MCF-7, RPE, Fibroblast, HEKn, TF-1, GM12878, IMR-90, SK-N-SH, Neutrophil, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 11% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES,Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 43%, "7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, PAX3-FOXO1, GATA6, RUNX2, ZFX, EZH2, MCM3, HIF1A, BRD4, ZSCAN5A, E2F1, PRDM9, ZNF334, CTCF, SPI1, MITF, AHR, YY1

Target gene symbol (double-evidenced CRMs): VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000157538,

eachgene

Deatailed information for cohesin site CDBP00419122