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Basic information

CohesinDB ID: CDBP00419126

Locus: chr21-38252145-38252348

Data sourse: ENCSR000BTQ, ENCSR703TNG, GSE72082

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 65%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF621, XBP1, FOXA1, SUZ12, HDGF, BMI1, NFIC, ATF3, RUNX3, PRDM1, PAX5, HDAC3, MAF, ELF1, TRIM28, BCLAF1, KLF6, TEAD1, ZNF217, ESR1, HNF1B, ZIK1, CTCF, TCF12, BAF155, E4F1, EP300, MNT, GATA6, DPF2, PAX8, IRF4, RAD51, ZNF512B, ZNF776, FOXA3, PDX1, EED, YBX1, GLIS1, POU2F2, ZNF239, POU5F1, TOP2A, MTA2, ZBTB17, SAP130, NBN, ARID3A, HNF4G, ERG, MYC, ONECUT1, RAD21, RXRA, BATF3, GABPA, XRCC5, ZNF398, IKZF1, NR3C1, EZH2, GRHL2, HES1, SPI1, IRF1, HDAC2, GATA2, GATAD2B, SIX2, SMARCA5, RELB, RUNX1, SMC1A, CEBPA, SIN3A, ZFX, AFF4, ZNF770, ERG3, TRIM22, GATA4, ARNT, BACH1, ATF2, PRDM9, MED1, ZEB1, MYB, PIAS1, STAT5A, BCL11A, SP1, NIPBL, HNF4A, REST, ATF7, FOXP1, NCOR2, MLLT1, NFATC3, MEF2B, PPARG, FOXA2, MTA3, EBF1, CREM, NFATC1, ZNF662, ZBTB33, HOXB13, BCL3, YY1, RELA, TARDBP, ZNF148, JUNB, ZNF521, SKIL, ZNF311, GATA3, BATF, TAL1, MAX, ZSCAN26, GATA1, ZNF143, TLE3, KLF4, ZNF592, NCOA3, NR2F2, ZNF544, NR2F1, TCF7L2, ZNF687, PKNOX1, ZNF334, BCL6B, PHOX2B, ELF3, TBX21, BHLHE40, AR, ZNF366, EGR1, IKZF2, BRD4, JUND, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): VPS26C,KCNJ15,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000157538, ENSG00000157542, ENSG00000157551,

eachgene

Deatailed information for cohesin site CDBP00419126