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Basic information

CohesinDB ID: CDBP00419127

Locus: chr21-38253333-38253633

Data sourse: ENCSR000BTQ, GSE72082, GSE98367, GSE101921, ENCSR000EDE, GSE103477, ENCSR703TNG, GSE25021

Cell type: MCF-7, HMEC, HeLa-S3, THP-1, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 63%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, ZNF384, SMC1A, RAD21, STAG2, TP53, SCRT1, BRD4, MYOD1, TAL1, CTCF, STAG1

Target gene symbol (double-evidenced CRMs): KCNJ15,VPS26C,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000157538, ENSG00000157542, ENSG00000157551,

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Deatailed information for cohesin site CDBP00419127