- Basic information
- CohesinDB ID: CDBP00419140
- Locus: chr21-38299358-38300863
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Data sourse: GSE206145-NatGen2015, ENCSR230ZWH
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Cell type: Liver, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 23%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, CBX5, SOX2, NME2, XBP1, FOXA1, MLL4, ATF3, NFIC, BMI1, ZFP64, ZNF362, ZBTB44, CHD7, RUNX3, PRDM1, ZNF189, TP63, ZSCAN4, JMJD1C, MYOG, MAF, ELF1, TRIM28, ETV1, SNAI2, ESR1, TP73, JUN, TCF12, CTCF, EP300, MNT, GATA6, SOX5, IRF4, E2F1, TEAD4, FOXA3, TFAP2C, POU2F2, CHD8, ZSCAN5D, POU5F1, BRD3, MYCN, MTA2, ZBTB48, ZSCAN5A, STAT1, MLLT3, DDX5, HNF4G, ERG, ETS1, MYC, SMARCA4, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, XRCC5, UBN1, NFE2, RCOR1, DACH1, VDR, ZNF750, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, ZNF652, GABPB1, ZHX2, SPI1, IRF1, GATA2, SSRP1, SIX2, FLI1, NFIL3, MYF5, ETV5, RUNX1, SMC1A, MAFG, CEBPA, EZH2phosphoT487, AFF4, ZFX, POU4F2, SMAD3, CBX8, SMARCC1, ZBTB2, ZNF384, CREBBP, NOTCH1, RUNX2, CDK6, GATA4, OSR2, PBX4, ARNT, SMAD4, ETV6, PBX3, FOS, CHD1, MED1, GMEB1, MYB, ZMYM3, PIAS1, SUPT16H, C11orf30, NCOA1, MAFK, SP1, BCL11A, NIPBL, HNF4A, ARID2, REST, TCF3, FOXP1, SMC3, ELL2, ETV4, PPARG, FOXA2, ZNF316, TBL1X, SS18, NFATC1, WT1, MAFF, FOXF1, ZBTB33, CDK9, BCL3, KDM1A, YY1, RELA, SP140, ZFP36, HIF1A, GATA3, BATF, TAL1, MAX, MAF1, SPIB, GATA1, ZNF143, NCOA3, NR2F2, NEUROG2, KDM5B, TP53, PKNOX1, MYOD1, PHOX2B, ELF3, BRD2, TBX21, BHLHE40, AR, EGR1, HSF1, ZBTB26, NOTCH3, JUND, BRD4, RNF2, CUX1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): DYRK1A,KCNJ6,KCNJ15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2191
- Number of somatic mutations (non-coding): 313
- Related genes and loops