- Basic information
- CohesinDB ID: CDBP00419142
- Locus: chr21-38309457-38313340
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Data sourse: ENCSR230ZWH, ENCSR501LQA, ENCSR760NPX, ENCSR150EFU, ENCSR000ECS, GSE111537, ENCSR330ELC, GSE108869, ENCSR917QNE, GSE206145-NatGen2015, ENCSR806UKK, GSE120943, ENCSR199XBQ, ENCSR895JMI, GSE98367, ENCSR193NSH, ENCSR768DOX, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE126755, ENCSR748MVX
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Cell type: RPE, Macrophage, Fibroblast, Monocytes, A-549, OCI-AML-3, HeLa-S3, Liver, Neutrophil, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX2, GRHL3, ESR1
- Target gene symbol (double-evidenced CRMs): KCNJ6,KCNJ15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 28
- Related genes and loops