- Basic information
- CohesinDB ID: CDBP00419148
- Locus: chr21-38341496-38342080
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, ZFX, XBP1, WT1, RELA, JUNB, MYC, RUNX2, GRHL3, MECOM, STAT3, MAX, XRCC5, TAL1, FOS, MED1, CEBPB, ZEB1, ESR1, ZNF334, NFKB1, CTCF, JUN, AR, TAF1, HSF1, BRD4, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): KCNJ6,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157542,
- Related loop:
chr21:36125000-36150000~~chr21:38325000-38350000,
chr21:36625000-36650000~~chr21:38325000-38350000,
chr21:37150000-37175000~~chr21:38325000-38350000,
chr21:37675000-37700000~~chr21:38325000-38350000,
chr21:37700000-37725000~~chr21:38325000-38350000,
chr21:37725000-37750000~~chr21:38325000-38350000,
chr21:37850000-37875000~~chr21:38325000-38350000,
chr21:37900000-37925000~~chr21:38325000-38350000,
chr21:38025000-38050000~~chr21:38325000-38350000,
chr21:38050000-38075000~~chr21:38325000-38350000,
chr21:38150000-38175000~~chr21:38325000-38350000,
chr21:38200000-38225000~~chr21:38325000-38350000,
chr21:38225000-38250000~~chr21:38325000-38350000,
chr21:38343298-38344481~~chr21:39136825-39139305,