- Basic information
- CohesinDB ID: CDBP00419152
- Locus: chr21-38365365-38365661
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Data sourse: GSE111913, GSE86191
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Cell type: RT-112, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: EZH2phosphoT487, MYCN, ZFX, XBP1, FOXA1, RELA, ASCL1, NEUROD1, AHR, EZH1, MYC, SMARCA4, OTX2, SMC3, MAX, HAND2, MED1, NCOA3, TRIM28, SCRT2, ESR1, PHOX2B, CTCF, SPI1, PAX3-FOXO1, NOTCH3, BRD4, SCRT1, MAZ, TEAD4, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): HLCS,PSMG1,KCNJ6,TTC3,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157542,
ENSG00000157554,
ENSG00000183527,
- Related loop:
chr21:36125000-36150000~~chr21:38350000-38375000,
chr21:36500000-36525000~~chr21:38350000-38375000,
chr21:36925000-36950000~~chr21:38350000-38375000,
chr21:37150000-37175000~~chr21:38350000-38375000,
chr21:37550000-37575000~~chr21:38350000-38375000,
chr21:37650000-37675000~~chr21:38350000-38375000,
chr21:37675000-37700000~~chr21:38350000-38375000,
chr21:37700000-37725000~~chr21:38350000-38375000,
chr21:37725000-37750000~~chr21:38350000-38375000,
chr21:37750000-37775000~~chr21:38350000-38375000,
chr21:37875000-37900000~~chr21:38350000-38375000,
chr21:37900000-37925000~~chr21:38350000-38375000,
chr21:37925000-37950000~~chr21:38350000-38375000,
chr21:38025000-38050000~~chr21:38350000-38375000,
chr21:38050000-38075000~~chr21:38350000-38375000,
chr21:38150000-38175000~~chr21:38350000-38375000,
chr21:38200000-38225000~~chr21:38350000-38375000,
chr21:38225000-38250000~~chr21:38350000-38375000,
chr21:38350000-38375000~~chr21:38575000-38600000,
chr21:38350000-38375000~~chr21:39125000-39150000,
chr21:38350000-38375000~~chr21:39150000-39175000,