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Basic information

CohesinDB ID: CDBP00419153

Locus: chr21-38375250-38375602

Data sourse: GSE72082, GSE73207

Cell type: MCF-7, TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 74%, "14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, SOX2, KDM4B, FOXA1, LEO1, TFAP4, LYL1, ATF3, NFIC, ZFP64, PRDM1, CBFB, MECOM, SMARCE1, TP63, CDX2, JMJD1C, ZNF629, TEAD1, TRIM28, ELF1, SNAI2, LMO2, ESR1, PITX3, JUN, TCF12, CTCF, KLF1, LMO1, ZNF75A, GATA6, DPF2, SMC1, TEAD4, EHMT2, TFAP2C, RBPJ, CHD8, MYCN, POU5F1, RUNX1T1, KDM4C, ZNF263, CTBP1, ZSCAN21, CDK7, ZBTB48, ZSCAN5A, STAT1, SRF, TBP, ERG, ETS1, MYC, TRIP13, SMARCA4, EZH1, RAD21, GRHL3, GABPA, STAT3, IKZF1, NFE2, RCOR1, ZNF639, NR3C1, CEBPB, ZNF750, KMT2A, CREB1, ZBTB11, EZH2, BMPR1A, EBF3, GABPB1, SPI1, GATA2, ZNF182, FLI1, NCOA2, RUNX1, CBX1, SMC1A, CEBPA, EZH2phosphoT487, LDB1, SIN3A, ZFX, AFF4, TET2, TRIM22, SMARCC1, PRDM10, CREBBP, ZNF35, RUNX2, OSR2, ZNF184, ARNT, NRF1, HMGB2, PBX3, FOS, SUPT5H, CDK8, MED1, ZEB1, DIDO1, KDM6B, MYB, EVI1, BCL11A, SP1, TFAP2A, NR4A1, ZBTB7A, POU2F3, HNRNPLL, TCF3, PRDM6, AATF, SMC3, STAG1, TRP47, PPARG, CBX3, TBL1X, CREM, MEIS1, EBF1, GTF2B, WT1, ZNF574, HOXB13, KDM1A, YY1, RELA, JUNB, AHR, SP140, HIF1A, GATA3, TAL1, GATA1, ZNF143, HAND2, SP7, NCOA3, NR2F2, TCF7L2, ZNF213, ZNF334, NFKB1, PHOX2B, AR, PAX3-FOXO1, ZBTB40, RXR, EGLN2, ZBTB42, ZNF366, HSF1, NOTCH3, BRD4, JUND, MAZ, TBX2, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): PSMG1,B3GALT5,KCNJ6,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527, ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419153