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Basic information

CohesinDB ID: CDBP00419156

Locus: chr21-38383484-38384452

Data sourse: GSE206145, GSE111913, GSE67783, GSE86191

Cell type: RPE, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 34%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, SUZ12, LEO1, TFAP4, LYL1, MECOM, JMJD1C, TRIM28, ZNF573, LMO2, ESR1, OCA2, CTCF, TCF12, BAF155, KLF1, POU5F1, ZNF263, MYCN, TOP2A, RUNX1T1, ZBTB48, STAT1, ERG, PBX1, ASCL1, OGG1, ETS1, MYC, SMARCA4, RAD21, GRHL3, GABPA, IKZF1, NFE2, NR3C1, CEBPB, KMT2A, EZH2, GRHL2, SPI1, INTS13, GATA2, FLI1, RUNX1, SMC1A, CEBPA, EZH2phosphoT487, ZFX, NFKBIA, TET2, ERG3, CBX8, NOTCH1, CDK6, ARNT, SUPT5H, CDK8, ZEB1, TEAD3, MYB, SMAD1, EVI1, HNF4A, NR4A1, ASH2L, TCF3, SMC3, MLLT1, STAG1, SKI, TRP47, PPARG, FOXA2, WT1, MEF2C, CDK9, KDM1A, YY1, RELA, NEUROD1, SP140, HIF1A, OTX2, TAL1, CBX2, NR2F1, TCF7L2, ZNF334, AR, HSF1, RNF2, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): B3GALT5,PSMG1,KCNJ6,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2440

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527, ENSG00000183778,

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Deatailed information for cohesin site CDBP00419156