- Basic information
- CohesinDB ID: CDBP00419161
- Locus: chr21-38394330-38394741
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: LEO1, FLI1
- Target gene symbol (double-evidenced CRMs): ERG,PSMG1,B3GALT5,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 40
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
ENSG00000183527,
ENSG00000183778,
- Related loop:
chr21:37725000-37750000~~chr21:38375000-38400000,
chr21:38050000-38075000~~chr21:38375000-38400000,
chr21:38375000-38400000~~chr21:38500000-38525000,
chr21:38375000-38400000~~chr21:38525000-38550000,
chr21:38375000-38400000~~chr21:38575000-38600000,
chr21:38375000-38400000~~chr21:38625000-38650000,
chr21:38375000-38400000~~chr21:38650000-38675000,
chr21:38375000-38400000~~chr21:38675000-38700000,
chr21:38375000-38400000~~chr21:38700000-38725000,
chr21:38375000-38400000~~chr21:39100000-39125000,
chr21:38375000-38400000~~chr21:39125000-39150000,
chr21:38375000-38400000~~chr21:39150000-39175000,
chr21:38375000-38400000~~chr21:39600000-39625000,
chr21:38388533-38390282~~chr21:39174059-39176516,