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Basic information

CohesinDB ID: CDBP00419162

Locus: chr21-38402377-38402598

Data sourse: GSE111913, GSE68388

Cell type: RT-112, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 36%, "14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NFIA, CBFA2T2, PPARG, ZSCAN5D, EZH2phosphoT487, MYCN, POU5F1, KDM4C, ZFX, POU4F2, TOP2A, ZNF263, WT1, ZSCAN5A, XBP1, FOXA1, CBX8, SUZ12, LEO1, CDK9, HOXB13, ERG, YY1, RELA, ZNF384, ASCL1, NEUROD1, ETS1, MYC, CDK6, SMARCA4, JUNB, NFIC, ARNT, HIF1A, NFIB, GRHL3, OTX2, GATA3, GABPA, TAL1, STAT3, TP63, FOS, MITF, RCOR1, HAND2, PLAG1, ZNF750, MYB, KMT2A, SNAI2, TFAP2C, EZH2, LMO2, ESR1, ZNF334, USF2, NFKB1, PHOX2B, CTCF, JUN, USF1, BCL11A, SPI1, ELF3, GATA2, ZNF479, IRF4, SREBF1, ASH2L, RAD51, RNF2, BRD4, SCRT1, MAZ, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 143

Number of somatic mutations (non-coding): 13

Related genes and loops

Related gene: ENSG00000157554,

eachgene

Deatailed information for cohesin site CDBP00419162