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Basic information

CohesinDB ID: CDBP00419164

Locus: chr21-38404289-38404685

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRIM25, CBFA2T2, CBX1, POU2F2, ZSCAN5D, POU5F1, EBF1, MYCN, SIRT6, ZFX, RUNX1T1, XBP1, ZBTB48, WT1, SRF, LEO1, ERG, YY1, RELA, PBX1, ATF3, MYC, GRHL3, HMGB2, XRCC5, IKZF1, NR3C1, MYB, KMT2A, NR2F1, EZH2, KDM5B, ESR1, MED, CTCF, BCL11A, SPI1, AR, FLI1, NOTCH3, BRD4, TCF3, FOXP1, MAZ, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): ERG

Function elements

Human SNPs: B-cell_acute_lymphoblastic_leukaemia_(high-hyperdiploidy)

Number of somatic mutations (coding): 22

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157554,

eachgene

Deatailed information for cohesin site CDBP00419164