- Basic information
- CohesinDB ID: CDBP00419168
- Locus: chr21-38413939-38415446
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR879KXD, ENCSR703TNG, ENCSR000ECS, GSE115602
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Cell type: K-562, HeLa-S3, MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, PBX2, ATF3, ATF4, SMARCE1, TEAD1, E2F5, ZNF217, ESR1, HDAC8, USF2, JUN, EP300, KLF1, TRIM24, SOX6, ZNF350, TEAD4, ZNF175, EHMT2, TFAP2C, RBPJ, TOP2A, ID3, CTBP1, ZNF317, ZBTB17, ZBTB48, TBP, MYC, SMARCA4, ARID1B, RAD21, IKZF1, RCOR1, NR3C1, ESRRA, CEBPB, EZH2, GRHL2, SPI1, HDAC2, GATA2, EP400, MYF5, CBX1, HDAC1, CEBPA, AFF4, ZFX, SIN3A, ZNF549, PRDM10, ZXDC, GATA4, ARNT, BACH1, ATF2, ZEB2, ZNF518A, NR2C1, SUPT5H, ZNF584, DIDO1, PIAS1, L3MBTL2, BCL11A, TFAP2A, REST, RBM25, ATF7, CTBP2, AFF1, FOXA2, MTA3, EBF1, MIER2, ZNF589, RELA, AHR, ZFP36, SKIL, HIF1A, GATA3, MAX, MTA1, CEBPG, GFI1B, ZKSCAN8, NR2F1, BCL6B, MYOD1, AR, TAF1, ZNF579, ZBTB40, EGLN2, RNF2, BRD4, JUND, IRF9, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 88
- Number of somatic mutations (non-coding): 0
- Related genes and loops