- Basic information
- CohesinDB ID: CDBP00419172
- Locus: chr21-38423063-38423584
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Data sourse: GSE120943, GSE67783, GSE98367
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Cell type: Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZSCAN5D, POU5F1, MYCN, KDM4C, ZFX, ZSCAN16, XBP1, ZBTB48, WT1, ZSCAN5A, FOXA1, LEO1, ERG, YY1, RELA, ASCL1, NEUROD1, ETS1, MYC, ATF3, SMARCA4, OSR2, AHR, SP140, ARNT, HIF1A, GRHL3, OTX2, GABPA, MECOM, TAL1, MAX, ZSCAN4, ZNF398, SUPT5H, ZNF143, CDX2, NCOA3, SCRT2, EZH2, ESR1, OCA2, BCL6B, MYOD1, BRD2, CTCF, AR, ASH2L, NCOR1, SCRT1, BRD4, E2F1, SMC1, ZNF350, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 814
- Number of somatic mutations (non-coding): 0
- Related genes and loops