- Basic information
- CohesinDB ID: CDBP00419173
- Locus: chr21-38424139-38424811
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Data sourse: GSE67783, GSE98367, ENCSR404BPV, GSE120943, ENCSR198ZYJ
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Cell type: Monocytes, Neurons-H1, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, SMC1A, ZSCAN5D, MYCN, MTA3, PPARG, SOX2, NME2, ZFX, POU4F2, LEO1, ZNF596, ERG, RELA, PBX1, NEUROD1, MYC, SMARCA4, GRHL3, OTX2, ATF2, MAX, HAND2, PLAG1, NR3C1, KMT2A, MYB, SCRT2, EZH2, ESR1, TBX5, CTCF, EP300, GSPT2, REST, NOTCH3, JUND, BRD4, TCF3, SCRT1, MAZ, NCOR2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 0
- Related genes and loops