- Basic information
- CohesinDB ID: CDBP00419176
- Locus: chr21-38434434-38435810
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Data sourse: GSE138405, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE126990, GSE165895
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Cell type: RPE, Hela-Kyoto, Fibroblast, SK-N-SH, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 35%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX7, POU2F2, ZSCAN5D, ZFX, NME2, XBP1, FOXA1, LEO1, ARNT, HMGB2, ZEB2, TAL1, MAX, MED1, ZEB1, KMT2A, SNAI2, ESR1, NOTCH3, BRD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 154
- Number of somatic mutations (non-coding): 0
- Related genes and loops