- Basic information
- CohesinDB ID: CDBP00419177
- Locus: chr21-38436999-38437515
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, PGR, FOSL1, SOX2, XBP1, FOXA1, LEO1, TFAP4, ATF3, NFIC, CHD7, PRDM1, CBFB, MECOM, TP63, JMJD1C, TEAD1, TRIM28, ETV1, SNAI2, NFE2L2, LMO2, ESR1, MLL, MED26, USF2, JUN, TCF12, CTCF, EP300, GATA6, SOX4, RFX5, DEK, SMC1, TEAD4, TFAP2C, POU2F2, CHD8, BRD1, MYCN, ZNF263, TOP2A, CDK7, RUNX1T1, POU5F1, ZBTB48, ZSCAN5A, ZNF134, GATAD1, ERG2, TBP, ERG, PBX1, ASCL1, OGG1, ETS1, MYC, EZH1, SMARCA4, RAD21, GRHL3, RXRA, NKX2-1, STAT3, XRCC5, UBN1, PRDM14, IKZF1, RCOR1, NFE2, DNMT3B, VDR, NR3C1, CEBPB, KMT2A, CREB1, EZH2, EBF3, ZHX2, SPI1, GATA2, FLI1, MRTFB, NFIL3, MYF5, RUNX1, SMC1A, CEBPA, LDB1, AFF4, ZFX, SIN3A, POU4F2, SMAD3, TET2, ERG3, TWIST1, SMARCC1, CREBBP, ZNF384, RUNX2, GATA4, NRF1, BACH1, DAXX, HMGB2, SMAD4, HMBOX1, PBX3, FOXM1, ZNF10, SMARCB1, FOS, CDK8, MED1, CEBPD, MYB, ZMYM3, ZNF3, ZNF41, C11orf30, EVI1, USF1, BCL11A, MAFK, REST, ZBTB7A, ZNF479, RBM25, ZHX1, TCF3, ZNF623, SMC3, ELL2, NCOR2, STAG1, STAG2, SKI, NELFA, TRP47, CBFA2T2, ZNF316, FOXA2, MEIS1, CHD2, SS18, WT1, MAFF, ESR2, FOXF1, ZBTB33, HOXB13, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, ZFP36, HIF1A, GATA3, TAL1, MAX, GATA1, ZNF143, PLAG1, CBX2, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, MED, ZNF334, NFKB1, BRD2, BHLHE40, AR, TAF1, ZBTB40, YAP1, HSF1, NCOR1, BRD4, JUND, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 33
- Number of somatic mutations (non-coding): 0
- Related genes and loops