- Basic information
- CohesinDB ID: CDBP00419179
- Locus: chr21-38444745-38445563
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Data sourse: ENCSR000BTQ, ENCSR167MTG, GSE67783, GSE72082, GSE86191, ENCSR000BLY, ENCSR000BLS, ENCSR703TNG, GSE25021
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Cell type: MCF-7, HCT-116, Hep-G2, SK-N-SH, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 42%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RBBP5, TOP2A, ZFX, DUX4, ERG3, LEO1, ERG, RELA, ETS1, MYC, CHD7, RAD21, GRHL3, NKX2-1, GABPA, ESR1, CTCF, PAX8, REST, GATAD2B, ASH2L, STAG1
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 836
- Number of somatic mutations (non-coding): 0
- Related genes and loops