- Basic information
- CohesinDB ID: CDBP00419180
- Locus: chr21-38448308-38449238
-
Data sourse: ENCSR000BLD, GSE101921, GSE138405, GSE115602
-
Cell type: MCF-7, H1-hESC, Hela-Kyoto, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 34%,
"7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, SOX2, XBP1, PBX2, ATF3, CHD7, MORC2, JMJD1C, MAF, TRIM28, ETV1, LMO2, MLL, PITX3, JUN, TCF12, CTCF, EP300, SMC1, TEAD4, KMT2B, JARID2, NANOG, CHD8, ZSCAN5D, POU5F1, TOP2A, ZBTB17, ERG, PBX1, ASCL1, ETS1, RAD21, GABPA, STAT3, PRDM14, IKZF1, NFE2, CEBPB, KMT2A, CREB1, EZH2, SPI1, HDAC2, INTS13, FLI1, RUNX1, CEBPA, ZFX, ZNF534, SMAD3, HMGB2, ATF2, PBX3, MED1, TERF1, MYB, SMAD1, USF1, NIPBL, BCL11A, SP1, NR4A1, REST, ASH2L, BCOR, FOXP1, SMC3, NCOR2, STAG1, SKI, CBFA2T2, HOXB13, KDM1A, YY1, RELA, JUNB, MCM3, ZIC2, HIF1A, PCGF1, TAL1, MAX, KLF4, NCOA3, TP53, PKNOX1, MED, ZNF334, T, AR, HSF1, RNF2, BRD4, JUND
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 88
- Number of somatic mutations (non-coding): 8
- Related genes and loops