- Basic information
- CohesinDB ID: CDBP00419181
- Locus: chr21-38455300-38455999
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Data sourse: GSE138405, GSE206145, GSE101921, GSE206145-NatGen2015, GSE126990
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Cell type: RPE, Hela-Kyoto, Fibroblast, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, ZFX, LEO1, TWIST1, MEF2A, RELA, JUNB, ZNF90, RUNX2, NFIC, ETS1, MYC, RAD21, NRF1, RXRA, GATA3, TAL1, PBX3, XRCC5, MAX, NR3C1, TEAD1, KMT2A, JUN, CTCF, TCF12, SPI1, EP300, REST, JUND, SMC1, TEAD4, FOSL2
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 55
- Number of somatic mutations (non-coding): 0
- Related genes and loops