- Basic information
- CohesinDB ID: CDBP00419183
- Locus: chr21-38467806-38468347
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BSB, GSE105028, GSE131606, GSE25021, ENCSR000BTU, ENCSR000BKV, GSE86191, GSE138405, GSE101921, ENCSR703TNG, GSE106870, GSE145327, ENCSR000BLS, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR000EDE, GSE131577
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Cell type: MCF-7, H1-hESC, HMEC, Hela-Kyoto, HCT-116, HL-60, Hep-G2, CVB-hiPSC, Ishikawa, DKO, HeLa-S3, HUES64, K-562, CVI-hiPSC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: SA1,Rad21,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 48%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, JARID2, SMC1A, CEBPA, POU5F1, RUNX1T1, POU4F2, SMAD3, FOXA1, PBX2, ERG, KDM1A, RELA, MYC, RAD21, GRHL3, PRDM9, MECOM, GATA1, NFE2, VDR, JMJD1C, PDX1, GFI1B, TRIM28, KMT2A, MYB, EZH2, LMO2, STAG1, EVI1, SETDB1, CTCF, TCF12, SPI1, BCL11A, NR4A1, AR, ZBTB16, GATA2, BRD4, TCF3, FOXP1, CLOCK, SMC3, KMT2B, STAG2, TFAP2C
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 11
- Number of somatic mutations (non-coding): 1
- Related genes and loops