- Basic information
- CohesinDB ID: CDBP00419184
- Locus: chr21-38468617-38469501
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Data sourse: ENCSR167MTG, GSE206145-GSE177045, GSE67783, GSE72082, GSE138405, ENCSR000BLS, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, GSE68388, GSE126990
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Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, Hep-G2, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
76% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, JARID2, SMC1A, CEBPA, POU5F1, RUNX1T1, POU4F2, SMAD3, FOXA1, PBX2, ERG, KDM1A, RELA, MYC, RAD21, GRHL3, PRDM9, MECOM, GATA1, NFE2, VDR, JMJD1C, PDX1, GFI1B, TRIM28, KMT2A, MYB, EZH2, LMO2, STAG1, EVI1, SETDB1, CTCF, TCF12, SPI1, BCL11A, NR4A1, AR, ZBTB16, GATA2, BRD4, TCF3, FOXP1, CLOCK, SMC3, KMT2B, STAG2, TFAP2C
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 77
- Number of somatic mutations (non-coding): 7
- Related genes and loops