Deatailed information for cohesin site CDBP00419188

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  • Basic information
  • CohesinDB ID: CDBP00419188
  • Locus: chr21-38475558-38475868
  • Data sourse: GSE206145, GSE86191
  • Cell type: RPE, HCT-116
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 76% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "14_ReprPCWk": 26%, "15_Quies": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, RXRB, MEN1, TEAD1, LMO2, OCA2, ARID5B, SOX5, PAX8, KMT2B, GATAD2A, NANOG, POU5F1, TOP2A, CTBP1, ERF, DUX4, STAT1, SAP130, ERG, SMARCA4, RCOR1, NR2F6, CEBPB, CREB1, BMPR1A, ZHX2, MIXL1, GATA2, ZNF644, FLI1, DRAP1, ZNF785, RUNX1, CEBPA, HDAC1, SP5, SMARCC1, PRDM10, ATF2, FOXM1, SP2, ZNF584, PML, PIAS1, SMAD1, NR1H2, EVI1, STAT5A, IKZF5, RBM25, AFF1, MBD2, CBFA2T2, CBX3, ZNF207, CREM, CHD2, NFATC1, ZSCAN16, WT1, MEF2C, JUNB, NEUROD1, MAF1, KLF4, BCL11B, ZKSCAN8, ZBTB6, MED, EGR2, ARID4B, RXR, EGLN2, HSF1, NCOR1, SCRT1, ZNF316, FOSL1, HNF1A, XBP1, KDM4B, PBX2, ATF3, CBFB, TP63, ZSCAN4, MITF, JMJD1C, INTS11, MAF, SNAI2, JUN, CTCF, LMO1, DPF2, IRF4, ZNF350, PDX1, MLX, TFAP2C, ZSCAN21, ZBTB17, MTA2, ZBTB48, ZNF317, NBN, PBX1, KDM4A, HOMEZ, RXRA, NKX3-1, LEF1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, TBL1XR1, GRHL2, ZSCAN29, SMARCA5, NFIL3, CC2D1A, THAP11, EZH2phosphoT487, LDB1, SOX13, AFF4, ZMIZ1, ARNT, ZNF48, HMBOX1, ZEB2, PBX3, ETV6, MAFB, HMGXB4, TEAD3, DIDO1, KLF9, TBX5, USF1, SP1, BCL11A, ATF7, ASH2L, CTBP2, PRDM6, SMC3, STAG2, STAG1, ZNF394, TRP47, MTA3, MEIS1, ZNF580, BCL3, KDM1A, ZIC2, GATA3, TAL1, NRIP1, ZNF143, TP53, NFKB1, PHOX2B, PHF5A, BRD2, KAT8, EGR1, RNF2, JUND, BRD4, PGR, SOX2, PATZ1, LEO1, TFAP4, CHD7, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, ESR1, TP73, KLF1, E2F6, TRIM24, RFX5, ZNF92, CDK9-HEXIM1, ZSCAN5D, ZSCAN5A, ERG2, HNF4G, ZNF114, OGG1, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, GFI1, EZH2, SPI1, HDAC2, INTS13, ETV5, BCL6, SIN3A, ERG3, MYBL2, RARA, ZNF384, CREBBP, HMGB2, SMAD4, CBFA2T3, CDK8, ZMYM3, NCOA1, ZNF22, MAFK, HNF4A, NR4A1, REST, BCOR, FOXP1, AATF, PPARG, ZNF692, ZNF662, TCF7, RELA, TARDBP, SKIL, MAX, GFI1B, NR2F1, TCF7L2, PKNOX1, MYOD1, AR, PAX3-FOXO1, ZBTB16, RBAK, ZNF395, AHR, DMAP1, FOSL2, HMG20A, E2F7, HMGN3, MEIS2, ZFHX2, LYL1, NFIC, CTCFL, PRDM1, MECOM, HDAC3, CDX2, TRIM28, ETV1, RCOR2, MLL, USF2, ZFP91, TCF12, EP300, BAF155, SOX6, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, CHD8, BRD1, MYCN, RUNX1T1, ID3, CDK7, GATAD1, ASCL1, ZNF341, RAD21, GRHL3, PROX1, ZNF614, XRCC5, NFE2, ZNF639, ZNF750, FEZF1, HES1, TFE3, EHF, IRF1, ZGPAT, ATF1, CBX1, SMC1A, ZNF335, ZFX, SMAD3, CBX8, NOTCH1, RUNX2, CDK6, GATA4, OSR2, ZNF184, NRF1, NR2C1, FOS, SUPT5H, MED1, CEBPD, ZNF558, MYB, SCRT2, VEZF1, L3MBTL2, SETDB1, KLF16, ZBTB7A, CCNT2, POU2F3, PHIP, TCF3, SKI, PAX7, FOXA2, RBBP5, MIER2, ZBED1, CDK9, HOXB13, ZNF589, YY1, ZNF148, SP140, HIF1A, GATA1, CEBPG, SP7, NCOA3, NR2F2, BHLHE40, ZBTB40, MYNN, MAZ, MEF2D, ZNF24
  • Target gene symbol (double-evidenced CRMs): ERG,PSMG1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 11
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000157554, ENSG00000183527,
  • Related loop: chr21:38150000-38175000~~chr21:38450000-38475000, chr21:38150000-38175000~~chr21:38475000-38500000, chr21:38450000-38475000~~chr21:38700000-38725000, chr21:38450000-38475000~~chr21:38900000-38925000, chr21:38450000-38475000~~chr21:39000000-39025000, chr21:38450000-38475000~~chr21:39100000-39125000, chr21:38450000-38475000~~chr21:39125000-39150000, chr21:38475000-38500000~~chr21:38675000-38700000, chr21:38475000-38500000~~chr21:38875000-38900000, chr21:38475000-38500000~~chr21:39125000-39150000, chr21:38475000-38500000~~chr21:39150000-39175000, chr21:38475839-38477375~~chr21:39125156-39127107,
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