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Basic information

CohesinDB ID: CDBP00419200

Locus: chr21-38496136-38496508

Data sourse: ENCSR000BLD, GSE101921

Cell type: H1-hESC, HCAEC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 76% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 26%, "15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, TRIM25, PGR, HMG20A, ZSCAN5C, SOX2, MEIS2, XBP1, FOXA1, LEO1, PBX2, MLL4, HNRNPK, MEN1, LYL1, ATF3, NFIC, CTCFL, CHD7, MORC2, CBFB, MECOM, PAX5, TP63, MITF, HDAC3, CDX2, JMJD1C, KLF5, ELF1, TRIM28, ETV1, SNAI2, LMO2, ESR1, MLL, TP73, ZNF561, JUN, TCF12, CTCF, EP300, BAF155, ZNF577, ZBTB20, LMO1, SOX5, GATA6, PAX8, KLF1, ZNF528, SMC1, TEAD4, FOXA3, PDX1, TFAP2C, RBPJ, EED, GLIS1, POU2F2, CHD8, NANOG, ZSCAN5D, POU5F1, ZNF263, RUNX1T1, TOP2A, BRD3, MYCN, ERF, CTBP1, DUX4, ZBTB48, STAT1, MLLT3, SRF, DDX5, ERG2, HOXC5, ERG, PBX1, ASCL1, OGG1, ETS1, MYC, ARID1B, RAD21, GRHL3, RXRA, NKX2-1, PROX1, GABPA, STAT3, UBN1, NKX3-1, IKZF1, RCOR1, NFE2, VDR, NR3C1, CEBPB, ZNF750, KMT2A, CREB1, EZH2, CBX1, GRHL2, BMPR1A, ZHX2, SPI1, EHF, IRF1, PCBP1, HDAC2, GATA2, ZNF182, MXD3, FLI1, PTBP1, RUNX1, SMC1A, ZBTB24, CEBPA, LDB1, EZH2phosphoT487, HDAC1, AFF4, ZFX, SOX13, SIN3A, SMAD3, PCBP2, TET2, CBX8, ERG3, SMARCC1, PRDM10, MEF2A, CREBBP, ZNF384, ZNF35, NOTCH1, RUNX2, CDK6, ZNF184, PBX4, DAXX, ARNT, HMGB2, PRDM9, HMBOX1, ZNF48, PBX3, FOXM1, CBFA2T3, SUPT5H, FOS, CDK8, MED1, TEAD3, PML, CEBPD, MYB, TERF1, PIAS1, ZMYM3, ZNF3, C11orf30, MAFG, TBX5, EVI1, STAT5A, KLF16, USF1, NIPBL, BCL11A, TFAP2A, HNF4A, SP1, MAFK, NR4A1, REST, ARID1A, RBM25, ASH2L, AFF1, TCF3, PHIP, FOXP1, BCOR, PRDM6, SMC3, ELL2, NCOR2, STAG1, STAG2, NFATC3, TRP47, CBFA2T2, ZNF316, FOXA2, PPARG, TBL1X, MEIS1, CBX3, EBF1, NFATC1, ZSCAN16, MAFF, WT1, ESR2, FOXF1, MEF2C, CDK9, HOXB13, ZNF318, KDM1A, YY1, RELA, TARDBP, JUNB, SP140, ZIC2, HIF1A, ZFP36, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, ZNF449, CBX2, TLE3, BCL11B, NCOA3, NR2F2, GFI1B, ZNF512, TCF7L2, KDM5B, TP53, MED, ZNF334, NFKB1, BCL6B, PHOX2B, BRD2, T, AR, ZBTB40, EGLN2, ZNF366, EGR1, HEXIM1, HSF1, NCOR1, RNF2, BRD4, JUND, NOTCH3, CLOCK, MAZ, MEF2D, ZFP42, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): PSMG1,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 55

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419200