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Basic information

CohesinDB ID: CDBP00419207

Locus: chr21-38519985-38520039

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 57%, "14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, POU2F2, CHD8, ZNF425, FOXA2, EZH2phosphoT487, CEBPA, MEIS1, ZNF496, NME2, ZFX, XBP1, SOX13, STAT1, FOXA1, MEF2C, PBX2, RXRB, ERG, RELA, PBX1, PRPF4, AHR, MYC, CDK6, RUNX2, HOMEZ, RUNX3, PRDM1, GRHL3, ARNT, CHD7, GATA3, ZNF48, GABPA, BATF, XRCC5, FOS, CDK8, JMJD1C, CEBPB, NCOA3, TEAD3, TRIM28, MYB, ZNF680, TEAD1, EZH2, ESR1, PKNOX1, MLL, ZNF334, STAT5A, CTCF, BCL11A, SPI1, SOX5, GATA2, ZNF644, IRF4, POU2F3, FOSL2, ZBTB26, NOTCH3, JUND, BRD4, NFIL3, FOXA3, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): PSMG1,ETS2,GET1,BRWD1,ERG,GET1-SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557, ENSG00000183527, ENSG00000185658, ENSG00000285815, ENSG00000182093,

eachgene

Deatailed information for cohesin site CDBP00419207