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Basic information

CohesinDB ID: CDBP00419209

Locus: chr21-38524127-38524519

Data sourse: ENCSR338DUC, GSE72082

Cell type: Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 60%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, HMG20A, SOX2, HNF1A, XBP1, FOXA1, HLF, RBFOX2, RXRB, SFMBT1, KDM3A, TFAP4, ZFHX2, THRB, NFIC, ZFP64, PRDM1, MXD4, ZSCAN4, ZNF320, CDX2, MAF, ZNF629, TEAD1, KLF6, KLF10, RCOR2, ESR1, JUN, EP300, LMO1, SOX5, GATA6, DMAP1, E2F6, IRF4, TEAD4, FOXA3, ZNF175, GATAD2A, GTF2F1, MLX, RBPJ, GLIS1, CHD8, ZNF263, HHEX, TOP2A, RUNX1T1, ZSCAN21, ZBTB17, ZNF563, GATAD1, SAP130, ARID3A, ERG2, TBP, HNF4G, ZBTB21, ONECUT1, MYC, HOMEZ, RAD21, GRHL3, RXRA, MCRS1, GABPA, XRCC5, ZNF614, UBN1, ZNF398, MIER3, ZNF667, NR2F6, CEBPB, CREB1, EZH2, TBL1XR1, KLF8, ZNF652, HES1, SPI1, MIXL1, TFE3, HDAC2, GATA2, INTS13, ZNF644, SIX2, DRAP1, ZGPAT, NFIL3, ZNF554, ETV5, RUNX1, THAP11, BCL6, CEBPA, EZH2phosphoT487, SOX13, ZFX, ZFP37, CBX8, TBX3, SP5, ERG3, SMARCC1, PRDM10, ZNF549, MYBL2, RARA, NFYC, CDK6, ARNT, ZNF48, SMAD4, FOS, HMGXB4, TEAD3, ZEB1, SCRT2, ZNF3, HIF2A, SP1, HNF4A, IKZF5, REST, ASH2L, PCGF2, TCF3, FOXP1, STAG1, ETV4, ZNF394, SKI, PPARG, FOXA2, ZNF316, CREM, MIER2, ZNF692, TCF7, ZNF580, FOXO3, KDM1A, YY1, RELA, ZFP36, HIF1A, TCF4, BATF, TAL1, MAX, NRIP1, ZNF143, TLE3, CEBPG, SP7, NCOA3, NR2F2, ZNF281, EGR2, ELF3, PHF5A, KAT8, NFKBIZ, ARID4B, AR, EGLN2, ZNF366, EGR1, ZBTB26, RNF2, NOTCH3, SCRT1, JUND, BRD4, MAZ, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): ETS2,ERG,BRWD1,PSMG1,GET1-SH3BGR,GET1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557, ENSG00000183527, ENSG00000185658, ENSG00000285815, ENSG00000182093,

eachgene

Deatailed information for cohesin site CDBP00419209