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Basic information

CohesinDB ID: CDBP00419214

Locus: chr21-38544663-38545173

Data sourse: GSE206145-NatGen2015, GSE68388

Cell type: Fibroblast, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PPARG, ZSCAN5D, MYCN, CEBPA, FOXA2, KDM4C, ZFX, SOX13, XBP1, ZBTB17, SMAD3, DUX4, FOXA1, HLF, SP5, KDM1A, RUNX2, CDK6, KDM4A, ZNF48, SMC3, MAX, PBX3, FOS, RCOR1, MED1, CEBPG, CEBPB, TEAD1, ZMYM3, EZH2, ESR1, CTCF, TCF12, KAT8, EHF, PAX3-FOXO1, SOX5, RBM25, FOSL2, HSF1, RNF2, NOTCH3, BRD4, E2F1, ZNF623, TEAD4, GATAD2A, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): B3GALT5,ERG,SH3BGR,PSMG1,KCNJ6,GET1-SH3BGR,LCA5L

Function elements

Human SNPs: .

Number of somatic mutations (coding): 28

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527, ENSG00000285815, ENSG00000157578, ENSG00000185437, ENSG00000183778,

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Deatailed information for cohesin site CDBP00419214