- Basic information
- CohesinDB ID: CDBP00419218
- Locus: chr21-38560926-38562459
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Data sourse: ENCSR054FKH, GSE72082, GSE206145-GSE177045
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Cell type: MCF-7, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 55%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HMG20A, XBP1, HNF1A, FOXA1, RXRB, NFIC, THAP1, HNRNPUL1, CHD7, MITF, HDAC3, CDX2, TEAD1, RCOR2, ESR1, MBD4, CTCF, JUN, BAF155, EP300, SOX5, E2F6, FOXA3, GATAD2A, TFAP2C, RBPJ, NANOG, CHD8, MYCN, HHEX, GATAD1, SAP130, ARID3A, ERG, ONECUT1, MYC, HOMEZ, GRHL3, XRCC5, NKX3-1, MIER3, NR2F6, NR3C1, ESRRA, CEBPB, EZH2, GRHL2, ZNF652, MIXL1, HDAC2, GATA2, ZGPAT, NFIL3, NCOA2, RUNX1, SMC1A, BCL6, CEBPA, SIN3A, SOX13, ZFX, SMAD3, TBX3, ERG3, CREBBP, RARA, ZNF384, ZNF48, SMAD4, CDK8, ZEB1, TEAD3, PIAS1, NCOA1, TFAP2A, ARID1A, ASH2L, PCGF2, FOXP1, SMC3, PPARG, FOXA2, CREM, WT1, HOXB13, KDM1A, RELA, BRG1, GATA3, MAX, NRIP1, TLE3, CEBPG, NCOA3, NR2F2, T, ELF3, KAT8, AR, ZBTB26, RNF2, NOTCH3, BRCA1, ZFP42, ZNF316
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 119
- Number of somatic mutations (non-coding): 0
- Related genes and loops