- Basic information
- CohesinDB ID: CDBP00419220
- Locus: chr21-38568732-38569349
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Data sourse: GSE206145-NatGen2015, GSE67783
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Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 44%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, PGR, SOX2, XBP1, FOXA1, SUZ12, ZBTB7B, CHD7, PRDM1, CBFB, ZNF189, HDAC3, MYOG, TRIM28, ESR1, PITX3, CTCF, TCF12, JUN, BAF155, EP300, ZNF260, GATA6, PAX8, E2F1, TEAD4, TFAP2C, JARID2, CHD8, POU5F1, MYCN, TOP2A, BRD3, ZNF263, ZBTB17, DUX4, ZBTB48, STAT1, ZNF134, ERG, PAX6, PBX1, MYC, RAD21, GRHL3, GABPA, NR3C1, CEBPB, KMT2A, EZH2, IRF1, HDAC2, ZNF146, FLI1, MRTFB, RUNX1, SMC1A, LDB1, EZH2phosphoT487, ZFX, POU4F2, TET2, SMARCC1, PRDM10, CREBBP, CBX4, RUNX2, ARNT, SOX11, PRDM9, ZNF10, MED1, SCRT2, ZMYM3, PIAS1, ZNF3, MAFK, BCL11A, RBM25, ASH2L, PCGF2, PHIP, TCF3, FOXP1, BCOR, ZNF623, SMC3, STAG1, FOXA2, TBL1X, ZNF692, WT1, HOXB13, KDM1A, YY1, RELA, AHR, SP140, ZIC2, HIF1A, OTX2, NRIP1, GATA1, ZNF143, TLE3, NCOA3, TP53, ZNF334, ZSCAN22, MYOD1, PHOX2B, BRD2, AR, PAX3-FOXO1, ZNF280D, ZBTB26, RNF2, NOTCH3, SCRT1, BRD4, MAZ, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 0
- Related genes and loops