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Basic information

CohesinDB ID: CDBP00419222

Locus: chr21-38576611-38576930

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 60%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PAX7, GLIS1, TRIM25, POU2F2, CHD8, FOSL1, ZSCAN5D, POU5F1, EZH2phosphoT487, MYCN, ID3, ZFX, ZNF263, XBP1, MAFF, DUX4, STAT1, FOXA1, ZBTB48, SRF, CBX8, WT1, TET2, ZSCAN5A, ZNF300, YY1, RELA, ASCL1, ZNF90, AHR, MYC, ATF3, SMARCA4, CHD7, PRDM1, ARNT, SP140, ZIC2, GRHL3, MCM3, MECOM, TAL1, PAX5, MAX, ZNF143, MITF, CEBPB, ZEB1, NCOA3, MYB, TFAP2C, NR2F1, CREB1, EZH2, ESR1, OCA2, C11orf30, GRHL2, ZNF334, TBX5, SREBF2, CTCF, MAFK, BCL11A, SPI1, LMO1, AR, ZNF257, NKX2-5, IRF4, ZBTB42, HSF1, NOTCH3, BRD4, E2F1, ZNF528, ZNF350, MAZ, SMC3, AATF, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,KCNJ6,GET1,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 21

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000285815, ENSG00000182093,

eachgene

Deatailed information for cohesin site CDBP00419222