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Basic information

CohesinDB ID: CDBP00419230

Locus: chr21-38599047-38599490

Data sourse: GSE206145, GSE86191

Cell type: RPE, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 40%, "14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, HMG20A, SOX2, NME2, XBP1, FOXA1, SUZ12, ZFHX2, ATF3, CHD7, ZSCAN4, MITF, CDX2, MYOG, TEAD1, TRIM28, ETV1, ZNF217, ESR1, LMO2, JUN, CTCF, BAF155, EP300, SOX5, DPF2, TEAD4, FOXA3, TFAP2C, GLIS1, BRD1, ZSCAN5D, POU5F1, MYCN, TOP2A, ZNF263, RUNX1T1, CTBP1, ZBTB48, ZSCAN5A, DUX4, SAP130, DDX5, ERG2, ERG, MYC, HOMEZ, GRHL3, PROX1, NKX2-1, GABPA, XRCC5, RCOR1, NR2F6, NR3C1, ESRRA, CEBPB, KMT2A, CREB1, EZH2, GRHL2, ZNF652, SPI1, TFE3, ZNF257, HDAC2, GATA2, FLI1, ZGPAT, RUNX1, CBX1, SMC1A, CEBPA, EZH2phosphoT487, SIN3A, ZFX, SMAD3, ERG3, CBX8, CREBBP, RARA, ARNT, PRDM9, CHD1, FOS, MED1, SPDEF, PIAS1, TFAP2A, ASH2L, CTBP2, FOXP1, STAG1, ZNF283, FOXA2, ZSCAN16, WT1, HOXB13, YY1, RELA, TARDBP, SP140, HIF1A, GATA3, MAX, NRIP1, CBX2, TLE3, NR2F2, KDM5B, TP53, ZBTB6, ZNF334, MYOD1, EGR2, PHOX2B, ELF3, AR, HSF1, RNF2, NCOR1, BRD4, JUND, NOTCH3, ZBTB26, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): ERG,GET1,KCNJ6,GET1-SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 25

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000285815, ENSG00000182093,

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Deatailed information for cohesin site CDBP00419230