- Basic information
- CohesinDB ID: CDBP00419231
- Locus: chr21-38601403-38601985
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Data sourse: GSE206145-GSE177045, GSE115602
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ESRRA, GATA2, EGLN2, EZH2, ARNT, ESR1, FOXA1, ZNF280A, CTCF, PRDM10, ZNF736
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 205
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157554,
- Related loop:
chr21:38050000-38075000~~chr21:38575000-38600000,
chr21:38150000-38175000~~chr21:38575000-38600000,
chr21:38350000-38375000~~chr21:38575000-38600000,
chr21:38375000-38400000~~chr21:38575000-38600000,
chr21:38400000-38425000~~chr21:38575000-38600000,
chr21:38575000-38600000~~chr21:38675000-38700000,
chr21:38575000-38600000~~chr21:38850000-38875000,
chr21:38575000-38600000~~chr21:38925000-38950000,
chr21:38575000-38600000~~chr21:39000000-39025000,
chr21:38575000-38600000~~chr21:39375000-39400000,
chr21:38600000-38625000~~chr21:38700000-38725000,