- Basic information
- CohesinDB ID: CDBP00419234
- Locus: chr21-38610373-38611557
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 46%,
"14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, POU2F2, CBFA2T2, SMC1A, ZSCAN5D, ZNF263, POU5F1, MYCN, KDM4C, ZFX, TBL1X, XBP1, EZH2phosphoT487, ZBTB48, WT1, ZSCAN5A, FOXA1, TET2, ERG3, CBX8, ZFHX2, TBP, YY1, RELA, ETS1, MYC, MCM3, RAD21, ARNT, SP140, PGR, STAT3, MAX, XRCC5, MED1, NR3C1, NCOA3, TRIM28, CREB1, EZH2, ESR1, CTCF, JUN, SPI1, ARRB1, BCL11A, AR, HSF1, BRD4, FOXP1, MAZ, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: Refractive_error
- Number of somatic mutations (coding): 250
- Number of somatic mutations (non-coding): 0
- Related genes and loops