- Basic information
- CohesinDB ID: CDBP00419236
- Locus: chr21-38619808-38623357
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE131606, GSE108869, GSE25021, GSE115602, ENCSR000BTU, GSE93080, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, GSE94872, ENCSR000EEG, GSE98367, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE129526, GSE111913, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE50893
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Cell type: GM2610, HuCC-T1, H9-hESC, GM2630, HMEC, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, HUVEC, GM19238, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 22% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.622
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, ZNF750, CEBPB, PGR, CREB1, CDK8, RCOR1
- Target gene symbol (double-evidenced CRMs): ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 385
- Number of somatic mutations (non-coding): 0
- Related genes and loops