- Basic information
- CohesinDB ID: CDBP00419238
- Locus: chr21-38628419-38628858
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Data sourse: ENCSR000BLD, GSE104888, GSE72082, GSE105028, GSE121355, GSE25021, GSE108869, ENCSR000EDW, GSE86191, GSE138405, GSE76893, ENCSR000EEG, ENCSR000BLS, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR054FKH, GSE68388
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HCT-116, Hep-G2, HeLa-S3, HUES64, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: BCL6, SMC1A, FOXA2, SIRT6, POU5F1, SOX2, NFATC1, TEAD4, POU4F2, ZBTB48, FOXA1, SRF, ERG2, HOXB13, BCL3, ERG, YY1, RELA, MYC, RUNX2, RAD21, ARNT, GRHL3, SMAD4, XRCC5, MAX, ZNF143, NR3C1, NCOA3, TEAD3, SCRT2, EZH2, TP53, ESR1, NCOA1, CTCF, AR, HDAC2, SMC1, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ERG,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops