- Basic information
- CohesinDB ID: CDBP00419240
- Locus: chr21-38636057-38637522
-
Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE206145-NatGen2015, ENCSR703TNG, GSE25021, GSE115602
-
Cell type: MCF-7, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 40%,
"14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA2, SIN3A, ZFX, CTBP1, DUX4, SMAD3, FOXA1, ZNF205, HOXB13, ZKSCAN1, ERG, CREBBP, NOTCH1, AHR, CHD7, RAD21, ARNT, GATA3, SMC3, STAT3, TP63, NRIP1, FOS, MED1, TLE3, NR3C1, ESRRA, NCOA3, TEAD1, TRIM28, NR2F2, TCF7L2, NR2F1, KDM5B, EZH2, ESR1, OCA2, GRHL2, TRPS1, CTCF, TCF12, EP300, TFAP2A, HNF4A, AR, DPF2, HDAC2, YAP1, GATA2, CTBP2, FOXP1, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): ERG,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 275
- Number of somatic mutations (non-coding): 0
- Related genes and loops