- Basic information
- CohesinDB ID: CDBP00419243
- Locus: chr21-38644766-38647197
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Data sourse: GSE86191, GSE206145, GSE85526, GSE206145-NatGen2015, GSE165895
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Cell type: RPE, Fibroblast, HCT-116, HEKn, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 37%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ZNF175
- Target gene symbol (double-evidenced CRMs): B3GALT5,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 300
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157554,
ENSG00000183778,
- Related loop:
chr21:37800000-37825000~~chr21:38650000-38675000,
chr21:38050000-38075000~~chr21:38650000-38675000,
chr21:38375000-38400000~~chr21:38625000-38650000,
chr21:38375000-38400000~~chr21:38650000-38675000,
chr21:38500000-38525000~~chr21:38625000-38650000,
chr21:38500000-38525000~~chr21:38650000-38675000,
chr21:38525000-38550000~~chr21:38625000-38650000,
chr21:38625000-38650000~~chr21:39600000-39625000,
chr21:38650000-38675000~~chr21:38750000-38775000,
chr21:38650000-38675000~~chr21:38800000-38825000,
chr21:38650000-38675000~~chr21:39000000-39025000,
chr21:38650000-38675000~~chr21:39125000-39150000,
chr21:38650000-38675000~~chr21:39150000-39175000,