- Basic information
- CohesinDB ID: CDBP00419249
- Locus: chr21-38675277-38675639
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Data sourse: GSE206145-NatGen2015, GSE67783
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Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 41%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, EZH2phosphoT487, ZNF263, TOP2A, SOX2, ZFX, XBP1, FOXA1, CBX8, SUZ12, ZNF300, HNRNPK, YY1, RELA, ZNF384, NOTCH1, ASCL1, MYC, SMARCA4, PRDM1, GRHL3, HIF1A, MAX, CBX2, NR3C1, EZH2, CTCF, SIX2, RNF2, PCGF2, MAZ, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
- Related loop:
chr21:37800000-37825000~~chr21:38650000-38675000,
chr21:38050000-38075000~~chr21:38650000-38675000,
chr21:38050000-38075000~~chr21:38675000-38700000,
chr21:38150000-38175000~~chr21:38675000-38700000,
chr21:38158438-38160422~~chr21:38679162-38680418,
chr21:38375000-38400000~~chr21:38650000-38675000,
chr21:38375000-38400000~~chr21:38675000-38700000,
chr21:38475000-38500000~~chr21:38675000-38700000,
chr21:38500000-38525000~~chr21:38650000-38675000,
chr21:38500000-38525000~~chr21:38675000-38700000,
chr21:38575000-38600000~~chr21:38675000-38700000,
chr21:38650000-38675000~~chr21:38750000-38775000,
chr21:38650000-38675000~~chr21:38800000-38825000,
chr21:38650000-38675000~~chr21:39000000-39025000,
chr21:38650000-38675000~~chr21:39125000-39150000,
chr21:38650000-38675000~~chr21:39150000-39175000,
chr21:38668369-38670536~~chr21:39135774-39139290,
chr21:38668432-38670423~~chr21:38711345-38713246,
chr21:38668432-38670423~~chr21:39135752-39139234,
chr21:38668443-38670408~~chr21:39125161-39127119,
chr21:38668443-38670408~~chr21:39135763-39136936,
chr21:38668443-38670408~~chr21:39136965-39139305,
chr21:38668443-38670408~~chr21:39174561-39176567,
chr21:38668473-38670334~~chr21:39136825-39139305,
chr21:38668492-38670300~~chr21:39137207-39139175,
chr21:38668589-38670460~~chr21:39137271-39139180,
chr21:38668612-38670314~~chr21:39135742-39136980,
chr21:38668612-38670314~~chr21:39174250-39176317,
chr21:38668618-38670577~~chr21:38711365-38713290,
chr21:38668618-38670577~~chr21:38795738-38797863,
chr21:38668618-38670577~~chr21:39125156-39127107,
chr21:38668618-38670577~~chr21:39135757-39139176,
chr21:38668646-38670341~~chr21:39135759-39139198,
chr21:38668658-38670293~~chr21:39135754-39136962,
chr21:38668658-38670293~~chr21:39137265-39139144,
chr21:38668670-38670341~~chr21:39135777-39139215,
chr21:38668681-38670318~~chr21:39136853-39139127,
chr21:38668743-38670427~~chr21:39135787-39137068,
chr21:38675000-38700000~~chr21:39125000-39150000,