Browse_each

Basic information

CohesinDB ID: CDBP00419250

Locus: chr21-38677433-38677813

Data sourse: GSE206145, GSE86191

Cell type: RPE, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, SMARCA2, MEIS2, FOXA1, PBX2, MLL4, ZFHX2, HNRNPK, TFAP4, ATF3, NFIC, RUNX3, PRDM1, CHD7, CBFB, MECOM, ZNF189, PAX5, JMJD1C, TEAD1, TRIM28, KLF6, ETV1, ESR1, MLL, HNF1B, CTCF, TCF12, JUN, BAF155, EP300, SIX5, IRF4, ZNF350, TEAD4, KMT2B, MYCN, POU5F1, TOP2A, KDM4C, RUNX1T1, ZNF317, MTA2, ZBTB48, DUX4, STAT1, SRF, DDX5, ARID3A, ERG, OGG1, ETS1, MYC, SMARCA4, RAD21, RXRA, GABPA, STAT3, VDR, NR3C1, ESRRA, CEBPB, KMT2A, CREB1, EZH2, GABPB1, SPI1, IRF1, PCBP1, GATA2, FLI1, HCFC1R1, MRTFB, RUNX1, SMC1A, ZBTB24, EZH2phosphoT487, ZFX, SMAD3, PCBP2, ERG3, CBX8, SMARCC1, PRDM10, MEF2A, RUNX2, PBX4, DAXX, ARNT, ZNF708, ATF2, HMBOX1, PBX3, FOS, CDK8, MED1, DIDO1, MYB, ZMYM3, BCL11A, SP1, REST, RBM25, ATF7, PCGF2, PHIP, BCOR, TCF3, MEF2B, TBL1X, CBX3, CREM, MEIS1, PAF1, SS18, EBF1, ZNF692, WT1, ESR2, MEF2C, CDK9, HOXB13, KDM1A, RELA, JUNB, ZFP36, GATA3, BATF, TAL1, MAX, KLF4, TCF7L2, NR2F1, TP53, PKNOX1, MED, ZNF334, EGR2, ELF3, TBX21, PAX3-FOXO1, AR, RXR, EGR1, RNF2, NOTCH3, BRD4, JUND, SCRT1, MEF2D, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): ERG,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554,

eachgene

Deatailed information for cohesin site CDBP00419250