- Basic information
- CohesinDB ID: CDBP00419252
- Locus: chr21-38683388-38683795
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Data sourse: GSE86191, GSE68388
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Cell type: HCT-116, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 41%,
"15_Quies": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, POU2F2, CHD8, CEBPA, EZH2phosphoT487, ZSCAN5D, TOP2A, SOX2, ZFX, POU4F2, XBP1, NME2, DUX4, WT1, RELA, CREBBP, MYC, CHD7, SP140, ARNT, ATF2, GATA3, GATA1, NR3C1, CEBPB, CEBPG, JMJD1C, CEBPD, TRIM28, EZH2, TP53, ESR1, CTCF, AR, GATA2, REST, MAZ, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): ERG,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
- Related loop:
chr21:38050000-38075000~~chr21:38675000-38700000,
chr21:38150000-38175000~~chr21:38675000-38700000,
chr21:38158438-38160422~~chr21:38679162-38680418,
chr21:38375000-38400000~~chr21:38675000-38700000,
chr21:38475000-38500000~~chr21:38675000-38700000,
chr21:38500000-38525000~~chr21:38675000-38700000,
chr21:38575000-38600000~~chr21:38675000-38700000,
chr21:38675000-38700000~~chr21:39125000-39150000,