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Basic information

CohesinDB ID: CDBP00419255

Locus: chr21-38696633-38696955

Data sourse: ENCSR000BLD, ENCSR000BTU, GSE72082, GSE86191, GSE138405, GSE110061, GSE129526, GSE25021, ENCSR000BLY, ENCSR000BLS, GSE105028, ENCSR000ECE, GSE68388, GSE112028, GSE103477, GSE145327, GSE108869, GSE94872, GSE97394

Cell type: MCF-7, H1-hESC, MDM, Hela-Kyoto, HCT-116, Hep-G2, Ishikawa, HUVEC, HeLa-S3, HUES64, SK-N-SH, HeLa-Tet-On, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.844

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 47%, "14_ReprPCWk": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: KLF4, E2F6, TRIM28, ZFX, RAD21, ESR1, WT1, SPI1, SMC3, CTCF, TBP, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): KCNJ6,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554,

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Deatailed information for cohesin site CDBP00419255