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Basic information

CohesinDB ID: CDBP00419265

Locus: chr21-38717916-38718385

Data sourse: GSE206145, GSE111913, GSE86191

Cell type: RPE, RT-112, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 70%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, CEBPA, LDB1, TOP2A, ZFX, DUX4, ERG, OGG1, JUNB, AHR, ATF4, NKX2-1, TAL1, CBFA2T3, FOS, GATA1, JMJD1C, CEBPB, TRIM28, MYB, LMO2, ZNF334, JUN, TCF12, SPI1, BCL11A, LMO1, AR, GATA2, FLI1, JUND, BRD4, TCF3, TEAD4, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): ERG,PSMG1,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527,

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Deatailed information for cohesin site CDBP00419265