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Basic information

CohesinDB ID: CDBP00419267

Locus: chr21-38722023-38723084

Data sourse: GSE86191, GSE111537, GSE67783, GSE68388

Cell type: OCI-AML-3, HCT-116, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, CHD8, CEBPA, MYCN, TOP2A, ZFX, XBP1, ZBTB48, WT1, YY1, ZNF384, NOTCH1, ATF3, RUNX2, MYC, SP140, GRHL3, ARNT, SMC3, PRDM9, CDK8, HNRNPH1, CEBPG, CEBPB, JMJD1C, TEAD3, TEAD1, TRIM28, MYB, CREB1, KMT2A, TP53, MLL, ESR1, ELF3, CTCF, SPI1, BCL11A, AR, REST, FLI1, HSF1, ZNF605, BRD4, TCF3, MAZ, TEAD4, STAG1

Target gene symbol (double-evidenced CRMs): ERG,PSMG1,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419267