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Basic information

CohesinDB ID: CDBP00419268

Locus: chr21-38724534-38724638

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GATA6, ZNF584, PAX8, VDR, CBX5, CBX3, TRIM28, TRIM24, PIAS1, ZNF317, GTF2B, GATA3, SETDB1, JUN, ZNF10, SPI1, RCOR1, DACH1

Target gene symbol (double-evidenced CRMs): ERG,KCNJ6,PSMG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419268