- Basic information
- CohesinDB ID: CDBP00419282
- Locus: chr21-38765117-38765356
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Data sourse: GSE67783, GSE98367
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Cell type: HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 59%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, PPARG, CEBPA, ZSCAN5D, MYCN, SIN3A, ZFX, POU4F2, XBP1, WT1, FOXA1, RELA, CREBBP, TCF4, GRHL3, BHLHE22, ZNF143, IKZF1, CEBPB, TRIM28, KMT2A, ESR1, OCA2, CTCF, SPI1, AR, BRD4, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): GET1,GET1-SH3BGR,KCNJ15,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000157551,
ENSG00000157554,
ENSG00000285815,
ENSG00000182093,
- Related loop:
chr21:34525000-34550000~~chr21:38750000-38775000,
chr21:38250000-38275000~~chr21:38750000-38775000,
chr21:38500000-38525000~~chr21:38750000-38775000,
chr21:38650000-38675000~~chr21:38750000-38775000,
chr21:38750000-38775000~~chr21:39100000-39125000,
chr21:38750000-38775000~~chr21:39375000-39400000,
chr21:38766321-38768490~~chr21:38787063-38788773,
chr21:38766338-38769337~~chr21:38787166-38788740,
chr21:38768038-38770235~~chr21:38795780-38799297,