Deatailed information for cohesin site CDBP00419283

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  • Basic information
  • CohesinDB ID: CDBP00419283
  • Locus: chr21-38766557-38767917
  • Data sourse: GSE93080, ENCSR167MTG, ENCSR000EAC, ENCSR000DZP, ENCSR230ZWH, GSE67783, GSE72082, GSE98367, GSE155324, ENCSR000BLS, ENCSR054FKH, GSE62063, ENCSR000BMY, GSE120943, GSE68388, GSE25021, GSE50893, GSE126755, ENCSR917QNE
  • Cell type: GM2610, Liver, HuCC-T1, GM2630, GM12890, GM2255, GM18486, GM18526, SNYDER, Monocytes, Lymphoblast, GM12878, GM12891, GM2588, GM19239, Macrophage, Ramos, GM12892, Hep-G2, GM19238, Neutrophil, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 9% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.756
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 96% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 24%, "7_Enh": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, CBX5, PGR, HMG20A, SOX2, NME2, FOXA1, RXRB, MLL4, KDM3A, HDGF, ATF3, NFIC, RUNX3, PRDM1, CHD7, ATF4, CBFB, MXD4, PAX5, ZSCAN4, BACH2, MAF, ELF1, TRIM28, BCLAF1, KLF6, SNAI2, RBM39, TEAD1, ZNF217, NFE2L2, ESR1, CTCF, TCF12, JUN, EP300, LMO1, SOX5, GATA6, DPF2, SOX4, DMAP1, SIX5, TRIM24, IRF4, E2F1, TEAD4, FOXA3, ZNF175, KMT2B, GATAD2A, RBPJ, EED, GLIS1, POU2F2, CHD8, MYCN, BRD3, CDK7, POU5F1, MTA2, ZBTB48, STAT1, GATAD1, SAP130, NBN, ARID3A, ERG, HOXC5, NFKB2, MYC, ONECUT1, SMARCA4, HOMEZ, RAD21, RXRA, NKX2-1, BATF3, GABPA, STAT3, ZNF614, XRCC5, IKZF1, RCOR1, MIER3, TERF2, NFE2, VDR, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, GABPB1, ZHX2, SPI1, TFE3, HBP1, IRF1, GATA2, ZNF644, MXD3, FLI1, DRAP1, ZGPAT, HCFC1, SMARCA5, MXI1, RELB, NFIL3, ATF1, ETV5, RUNX1, THAP11, CBX1, BCL6, CEBPA, LDB1, NKX2-2, SMC1A, SOX13, ZFX, AFF4, SMAD3, TET2, CBX8, SP5, SMARCC1, MEF2A, RARA, CREBBP, NOTCH1, IRF2, RUNX2, GATA4, ARNT, PBX4, ZNF48, ATF2, SMAD4, ZEB2, CBFA2T3, ETV6, FOXM1, SUPT5H, CDK8, FOS, PBX3, CHD1, MED1, TEAD3, ZEB1, TERF1, MYB, SUPT16H, STAT5A, MAFK, SP1, BCL11A, NIPBL, HNF4A, IKZF5, REST, ZBTB7A, ATF7, ASH2L, TCF3, BCOR, FOXP1, SMC3, NCOR2, STAG1, MLLT1, ETV4, NFATC3, PAX7, MEF2B, CBX3, FOXA2, EBF1, CREM, MTA3, E2F8, MIER2, SS18, GTF2B, WT1, FOXF1, MEF2C, CDK9, ZNF580, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, MCM3, SP140, TCF4, ZFP36, HIF1A, SKIL, BHLHE22, GATA3, BATF, TAL1, MAX, SPIB, GATA1, CBX2, KLF4, BCL11B, ZNF592, NCOA3, NR2F2, TCF7L2, KDM5B, TP53, PKNOX1, MED, NFKB1, ELF3, PHF5A, KAT8, BRD2, TBX21, ARID4B, PAX3-FOXO1, BHLHE40, AR, TAF1, ZBTB40, EGLN2, ZBTB26, RNF2, IKZF2, JUND, BRD4, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): KCNJ15,GET1-SH3BGR,ERG,GET1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 5
  • Related genes and loops
  • Related gene: ENSG00000157551, ENSG00000157554, ENSG00000285815, ENSG00000182093,
  • Related loop: chr21:34525000-34550000~~chr21:38750000-38775000, chr21:38250000-38275000~~chr21:38750000-38775000, chr21:38500000-38525000~~chr21:38750000-38775000, chr21:38650000-38675000~~chr21:38750000-38775000, chr21:38750000-38775000~~chr21:39100000-39125000, chr21:38750000-38775000~~chr21:39375000-39400000, chr21:38766321-38768490~~chr21:38787063-38788773, chr21:38766338-38769337~~chr21:38787166-38788740, chr21:38768038-38770235~~chr21:38795780-38799297,
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