- Basic information
- CohesinDB ID: CDBP00419286
- Locus: chr21-38772380-38772727
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE111913, GSE67783
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Cell type: RPE, Fibroblast, HSPC, RT-112
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 37%,
"5_TxWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CDX2, NR3C1, CEBPB, GATA2, GATA4, GRHL3, BRD4, SMAD3, STAT1, GATA3, FOXA1, ZNF334, PHIP, PHOX2B, PAX5, HNF4A
- Target gene symbol (double-evidenced CRMs): ERG,GET1-SH3BGR,GET1,KCNJ15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000157551,
ENSG00000157554,
ENSG00000285815,
ENSG00000182093,
- Related loop:
chr21:34525000-34550000~~chr21:38750000-38775000,
chr21:37850000-37875000~~chr21:38775000-38800000,
chr21:38250000-38275000~~chr21:38750000-38775000,
chr21:38500000-38525000~~chr21:38750000-38775000,
chr21:38650000-38675000~~chr21:38750000-38775000,
chr21:38750000-38775000~~chr21:39100000-39125000,
chr21:38750000-38775000~~chr21:39375000-39400000,
chr21:38766321-38768490~~chr21:38787063-38788773,
chr21:38766338-38769337~~chr21:38787166-38788740,
chr21:38768038-38770235~~chr21:38795780-38799297,
chr21:38775000-38800000~~chr21:39375000-39400000,
chr21:38775000-38800000~~chr21:41350000-41375000,
chr21:38775000-38800000~~chr21:43325000-43350000,