Deatailed information for cohesin site CDBP00419288

Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00419288
  • Locus: chr21-38775576-38776072
  • Data sourse: GSE206145-NatGen2015, ENCSR853VWZ, ENCSR956LGB
  • Cell type: Fibroblast, A-549
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: Mau2,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 96% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 68%, "14_ReprPCWk": 12%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, SMARCA2, E2F7, SOX2, NME2, XBP1, FOXA1, HLF, LEO1, ZFHX2, ATF3, NFIC, ZFP64, CHD7, RUNX3, KLF14, ZNF273, ZNF189, PAX5, BACH2, CDX2, MAF, ZNF629, ELF1, TRIM28, TEAD1, KLF6, SNAI2, NFE2L2, ESR1, OCA2, MLL, HNF1B, USF2, CTCF, JUN, TCF12, EP300, ZBTB20, MNT, DPF2, SOX4, E2F6, TRIM24, RFX5, IRF4, E2F1, TEAD4, FOXA3, GATAD2A, PDX1, RBPJ, EED, TFAP2C, POU2F2, CHD8, ZSCAN5D, ZNF263, MYCN, ZNF778, KDM4C, ZBTB17, ZBTB48, ZSCAN5A, STAT1, SAP130, ERG2, HOXC5, PBX1, SMARCC2, MYC, SMARCA4, RAD21, FOXP2, GRHL3, PROX1, NKX2-1, BATF3, STAT3, XRCC5, UBN1, ZNF398, IKZF1, RCOR1, ZNF639, VDR, NR3C1, CEBPB, KMT2A, EZH2, EBF3, ZHX2, SPI1, IRF1, KLF17, INTS13, GATA2, ZNF644, FLI1, MXI1, ZGPAT, MRTFB, ZNF554, RUNX1, SMC1A, CEBPA, EZH2phosphoT487, SIN3A, ZFX, ZNF534, ZNF132, SMAD3, TET2, ERG3, CBX8, SMARCC1, TWIST1, RARA, CREBBP, RUNX2, GATA4, ZNF184, GR, NRF1, PBX4, DAXX, HMGB2, ATF2, PRDM9, ETV6, PBX3, FOS, SMARCB1, CHD1, CDK8, MED1, ZEB1, TEAD3, MYB, NR1H2, SETDB1, STAT5A, USF1, NIPBL, MAFK, SP1, BCL11A, GSPT2, IKZF5, ZHX1, PHIP, TCF3, FOXP1, SMC3, HMGB1, STAG1, MEF2B, PPARG, FOXA2, CBX3, EBF1, CREM, SS18, ZNF600, ZNF692, ZSCAN16, ZBED1, MAFF, WT1, FOXF1, BCL3, KDM1A, ZNF19, RELA, YY1, JUNB, SP140, TCF4, ZFP36, HIF1A, ZNF311, GATA3, BATF, MGA, TAL1, MAX, ZNF143, GATA1, PLAG1, KLF4, SP7, NCOA3, NR2F2, NEUROG2, TCF7L2, NR2F1, TP53, MED, NFKB1, MYOD1, EGR2, ELF3, BRD2, BHLHE40, AR, TAF1, RNF2, IKZF2, BRD4, JUND, NOTCH3, MAZ, BRCA1, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): GET1,KCNJ6,GET1-SH3BGR
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 4
  • Related genes and loops
  • Related gene: ENSG00000157542, ENSG00000285815, ENSG00000182093,
  • Related loop: chr21:34525000-34550000~~chr21:38750000-38775000, chr21:37850000-37875000~~chr21:38775000-38800000, chr21:38250000-38275000~~chr21:38750000-38775000, chr21:38500000-38525000~~chr21:38750000-38775000, chr21:38650000-38675000~~chr21:38750000-38775000, chr21:38750000-38775000~~chr21:39100000-39125000, chr21:38750000-38775000~~chr21:39375000-39400000, chr21:38775000-38800000~~chr21:39375000-39400000, chr21:38775000-38800000~~chr21:41350000-41375000, chr21:38775000-38800000~~chr21:43325000-43350000,
eachgene