- Basic information
- CohesinDB ID: CDBP00419294
- Locus: chr21-38789235-38790110
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Data sourse: GSE206145-GSE177045, ENCSR153HNT, GSE86191
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Cell type: K-562, MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, NME2, FOXA1, HLF, RXRB, MLL4, KDM3A, ZBTB44, IKZF3, PAX5, TEAD1, LMO2, ZNF561, SOX5, DEK, E2F4, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, ZNF263, BRD3, CTBP1, DUX4, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, NFKB2, SMARCA4, FOXK2, UBN1, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, KLF17, ZNF257, GATA2, ZNF644, MXD3, DRAP1, MXI1, HCFC1, RUNX1, CEBPA, HDAC1, NKX2-2, TBX3, SP5, SMARCC1, PRDM10, ZNF549, ZXDC, ZBTB2, SOX11, ZBTB10, ATF2, FOXM1, SP2, SMARCB1, GMEB1, PML, TERF1, PIAS1, SMAD1, NR1H2, MBD1, STAT5A, IKZF5, RBM25, MBD2, ELL2, ETV4, NFATC3, CBFA2T2, CBX3, CREM, CHD2, PAF1, ZSCAN16, WT1, MEF2C, JUNB, NEUROD1, ZFP36, TCF4, BATF, PLAG1, ZFP69B, KLF4, ZBTB6, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, FOSL1, ZNF660, HNF1A, XBP1, ZNF101, PBX2, TSC22D4, ATF3, THRB, ZFP64, RUNX3, WDHD1, TP63, MITF, ZNF467, JMJD1C, ELF1, ZNF573, RBM39, SNAI2, KLF10, CTCF, JUN, TAF3, L3MBTL4, ZBTB20, MNT, LMO1, DPF2, ZNF423, ZNF350, PDX1, RBPJ, MLX, TFAP2C, ZSCAN21, ZBTB17, ZBTB48, MTA2, NONO, SRF, ONECUT1, TSHZ1, HOMEZ, RXRA, NKX3-1, MIER3, LEF1, HNRNPH1, VDR, NR3C1, ESRRA, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, SSRP1, ZNF146, NFIL3, THAP11, CTNNB1, ZBTB24, SOX13, AFF4, ZMIZ1, ZNF18, SP3, ARNT, DAXX, ZNF48, ZEB2, HMBOX1, NFYA, PBX3, ETV6, ZNF10, HMGXB4, TEAD3, ZXDB, ZNF680, U2AF1, KLF9, USF1, SP1, BCL11A, TFAP2A, ATF7, ASH2L, CTBP2, GLIS2, PRDM6, ZNF623, SMC3, STAT2, STAG1, ZNF394, TRP47, MTA3, EBF1, MAFF, ZNF580, BCL3, ZKSCAN1, KDM1A, ZNF19, KAT2B, ZIC2, GATA3, TAL1, NRIP1, ZNF143, MTA1, AGO2, ZNF768, TP53, NFKB1, ZSCAN22, BRD2, PHF5A, KAT8, EGR1, RNF2, BRD4, JUND, CUX1, ZSCAN23, SMAD4.1D12, PGR, CBX5, SOX2, PATZ1, TFAP4, SIN3B, CHD7, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, KLF1, SOX9, SOX4, E2F6, TRIM24, RFX5, PRKDC, GTF2F1, GLIS1, POU2F2, ZSCAN5D, ZNF778, KDM4C, ZBTB1, ZSCAN5A, ERG2, SP4, TBP, HNF4G, HOXC5, SMARCC2, ETS1, MYC, ARID1B, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, DNMT3B, INO80, EZH2, ZNF652, SPI1, ZNF786, HDAC2, INTS13, GATAD2B, NCOA2, ZNF554, ETV5, BCL6, SIN3A, ZFP37, ERG3, MEF2A, MYBL2, RARA, ZNF384, NFYC, ZNF35, CREBBP, SMAD4, ZNF518A, CBFA2T3, CDK8, ZEB1, ZNF264, ZMYM3, NCOA1, RBM22, MAFK, HNF4A, REST, ARID1A, ZHX1, HOXA9, FOXP1, NCOR2, PPARG, ZNF692, GTF2B, ZNF30, ZNF574, TCF7, FOXO3, ZNF318, RELA, TARDBP, MGA, MAX, ZNF592, GFI1B, NEUROG2, TCF7L2, KDM5B, NR2F1, PKNOX1, AR, PAX3-FOXO1, ZNF324, RBAK, ZNF280D, AHR, DMAP1, MBD3, FOSL2, ZNF391, HMG20A, ZSCAN5C, E2F7, MEIS2, RBFOX2, ZFHX2, INSM2, NFIC, PRDM1, KLF14, CDX2, ZNF629, KLF5, TRIM28, ETV1, RCOR2, HNF1B, USF2, TCF12, BAF155, EP300, GATA6, GLI4, SOX6, RAD51, E2F1, TEAD4, FOXA3, ZNF175, EHMT2, EED, MYCN, ID3, HINFP, GATAD1, GMEB2, ARID3A, ZNF341, RAD21, GRHL3, PROX1, APC, ZNF614, XRCC5, NFE2, ZNF639, ARNTL, ZNF750, TFE3, HBP1, IRF1, ZGPAT, ATF1, PTBP1, CBX1, SMC1A, FIP1L1, ZFX, ZNF335, SMAD3, TWIST1, IRF2, PRPF4, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, GR, PBX4, NRF1, FOS, CHD1, MED1, CEBPD, ZNF558, SCRT2, MYB, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, POU2F3, PHIP, TCF3, SKI, FOXA2, MIER2, ZNF600, ZBTB33, CDK9, HOXB13, YY1, ZNF148, BRCA1, SP140, HIF1A, GATA1, HAND2, TLE3, CEBPG, SP7, NCOA3, NR2F2, ZNF687, ZNF843, NFKBIZ, BHLHE40, TAF1, ZBTB40, ZBTB42, MYNN, NOTCH3, MAZ, ZNF440, ZNF24
- Target gene symbol (double-evidenced CRMs): GET1,GET1-SH3BGR,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops