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Basic information

CohesinDB ID: CDBP00419306

Locus: chr21-38846463-38848614

Data sourse: ENCSR000BTU, GSE206145-GSE177045, ENCSR230ZWH, GSE67783, GSE138405, GSE111913, ENCSR000BLY, ENCSR879KXD, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, ENCSR153HNT, GSE112028, GSE68388, GSE126990, GSE108869, GSE126755, ENCSR000ECS, ENCSR917QNE

Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, Ishikawa, HeLa-S3, RT-112, Liver, SK-N-SH, K-562, HeLa-Tet-On, Neutrophil, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.844

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, SOX2, MEIS2, XBP1, FOXA1, PBX2, UBTF, HDGF, ATF3, NFIC, TP63, MITF, KLF5, ETV1, ESR1, TP73, HDAC8, USF2, JUN, TCF12, CTCF, EP300, DPF2, E2F6, RFX5, CREB3, DEK, SOX6, RAD51, E2F4, DDX20, TEAD4, ZNF175, CHD8, MYCN, CTBP1, STAT1, TBP, HOXC5, ERG, ETS1, MYC, ONECUT1, SMARCA4, ARID1B, RAD21, FOXP2, RXRA, GABPA, STAT3, UBN1, RCOR1, DNMT3B, ZNF639, NFRKB, NR3C1, CEBPB, ZBTB11, EBF3, EHF, IRF1, HDAC2, GATA2, NCOA2, ATF1, CEBPA, HDAC1, ZFX, SMAD3, ERG3, ARNT, NRF1, BACH1, SOX11, PBX3, CBFA2T3, FOS, SMARCB1, TERF1, L3MBTL2, USF1, SP1, BCL11A, HNF4A, REST, PHIP, SMC3, NCOR2, STAG1, MLLT1, FOXA2, MTA3, CHD2, WT1, ZBTB33, ZNF589, YY1, RELA, JUNB, HIF1A, MGA, TAL1, MAX, GATA1, HAND2, PLAG1, KLF4, ZNF592, NCOA3, NR2F2, TCF7L2, NEUROG2, TP53, PKNOX1, NFKB1, BHLHE40, AR, HSF1, RNF2, NOTCH3, BRD4, JUND, MAZ, ZNF395

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419306